Glutathione S-Transferase T1 and M1: Gene Sequence Variation and Functional Genomics
نویسندگان
چکیده
منابع مشابه
Glutathione S-transferase T1 and M1: gene sequence variation and functional genomics.
PURPOSE The glutathione S-transferases (GSTs) catalyze the glutathione conjugation of reactive electrophiles, including carcinogens and many antineoplastic drugs. GSTT1 and GSTM1 are polymorphically deleted, but the full range of genetic variation in these two genes has not yet been explored. We set out to systematically identify common polymorphisms in GSTT1 and GSTM1, followed by functional g...
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1 Genetic Research Group, Molecular and Bioinformatics Unit, Department of Biomedical Science, Faculty of Medicine and Health Sciences, University Putra Malaysia, 43400 UPM Serdang, Selangor DE, Malaysia. 2 Department of Genetics, Faculty of Medicine, Tonekabon Islamic Azad University, Tonekabon, Mazandaran, Iran. 3 Department of Pathology, Faculty of Medicine and Health Sciences, University Pu...
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ژورنال
عنوان ژورنال: Clinical Cancer Research
سال: 2007
ISSN: 1078-0432,1557-3265
DOI: 10.1158/1078-0432.ccr-07-0635